What happens if I use too much niacinamide?
"When used in high concentrations, it can cause skin irritation and redness," Talakoub says. "Especially in sensitive areas such as around the eyes." Exactly how much niacinamide is too much depends on your genes and the sensitivity of your skin, explains cosmetic chemist Perry Romanowski.
You may experience some redness and irritation when you start using niacinamide products. Some of this may be normal and lessen over time, but lasting irritation may be a sign you're using too much or a product with too high of a concentration of niacinamide for your skin type.
Prescription products containing niacinamide are safe when taken as directed. Niacinamide-containing foods or supplements are safe when taken in doses lower than 35 mg daily. Niacinamide is possibly safe when taken in doses up to 900-1500 mg daily.
You're more likely to irritate your skin with ultrahigh concentrations than anything else." While the B vitamin is beloved for strengthening the skin barrier, too much of it can actually lead to sensitivity, skin irritation, and redness—but if you stick to a 2% to 5% concentration, you should be set.
Shirazi says that higher concentrations of niacinamide—“particularly those at 10% or higher—“can potentially cause irritation such as redness and rebound oil production.” On that note, Dr. Green recommends that sensitive-skinned folks start with a lower concentration to avoid potential irritation and redness.
3% to 6%: Improving tone, texture, and overall skin barrier, including hyperpigmentation and dull skin. Higher than 7%: This is too high and may lead to irritation, especially if you have sensitive skin.
How long will it take to see the results of niacinamide? While some niacinamide-containing products start to show initial benefits in two weeks, most results will show in four weeks or more.
Generally speaking, niacinamide can be used at any time of day—one to two times daily depending on the formulation—and generally in combination with other products without issue.
How long does niacinamide take to work? Generally speaking, you should start to see results after 2-4 weeks of twice daily usage (depending on the severity of your skin concerns and how concentrated your niacinamide product is). Ongoing use is required for continued improvement.
Niacinamide skincare products can sometimes cause breakouts in people who are acne-prone. If you start to experience more breakouts while using niacinamide products, discontinue use immediately.
What not to use with niacinamide?
Don't Mix: Niacinamide and vitamin C. Although they're both antioxidants, vitamin C is one ingredient that's not compatible with niacinamide. "Both are very common antioxidants used in a variety of skincare products, but they should not be used one right after the other," says Dr. Marchbein.
"An effective product should have between 2 and 10 percent niacinamide," she explains. Dr. Allenby adds that products with niacinamide concentrations under 5 percent are especially well-tolerated.
Dr. Li explains that "the scientific literature suggests 5% as optimal for achieving desired effects" and she goes further to caution that higher concentrations may cause skin irritation.
A typical purge lasts about as long as one skin cycle, which is four to six weeks, depending on your skin. Once that first skin cycle is over, your purge pimples should ease up, and you should start to notice the clarifying and brightening benefits of your new product.
In the clinical studies, niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use. Conclusions: The data suggest niacinamide is an effective skin lightening compound that works by inhibiting melanosome transfer from melanocytes to keratinocytes.
Apply your serum after cleansing (and toning, if you're a fan), and before heavier or oil-based serums, moisturiser and sunscreen. Applying oil-based serums first can impair the efficacy of your niacinamide serum, which will typically be water-based. So, use your Vitamin B3 first.
Because Niacinamide helps visibly fade age spots and dark spots, it does lighten the appearance of skin and is effective at managing discoloration.
Niacinamide reduces inflammation , which may help ease redness from eczema, acne, and other inflammatory skin conditions. Minimizes pore appearance. Keeping skin smooth and moisturized may have a secondary benefit — a natural reduction in pore size over time.
Moisturizing ingredients: damp skin
If your facial routine is simple and you're just applying a moisturizer after you cleanse, you'll want to do this ASAP, while your skin is still wet. The same goes for any moisturizing serums you may layer into your routine, like hyaluronic acid, squalene, or niacinamide.
You can combine niacinamide with all other serums and creams. You can use it with retinol, Hyaluronic acid, Vitamin C, BHAs, or AHAs. Niacinamide and retinol work well together.
How many days does niacinamide serum take to work?
7. How long does Niacinamide take to work? Using 5% or 10% Niacinamide-containing products show better effects with no skin problems like irritation. Most studies show that even though you may find improvement immediately after starting Niacinamide, it usually takes anywhere between 8-12 weeks for a visible change.
Topical niacinamide is generally considered safe to use. People who have preexisting allergies may be more likely to experience an allergic reaction. This is because niacinamide can cause your body to release histamine.
Absolutely, in fact, you can use niacinamide twice a day. This is because the ingredient is mild and stable enough to work effectively on the skin within a routine containing different actives.
Drop 2 drops of Niacinamide 10% Zinc 1% in your hands.
If you use too much of the product, you could cause irritation, especially if you have sensitive skin.
While some niacinamide-containing products start to show initial benefits in two weeks, most results will show in four weeks or more. "You have to remember that it doesn't take two days for spots to form so you can't expect them to be removed in two days either," explains Engelman.
In addition, niacinamide helps prevent premature signs of skin aging, including boosting collagen production to smooth wrinkles and reduce discolorations, says Nazarian. She recommends the ingredient for people with dry, sensitive, aging, or acne-prone skin.
Don't Mix: Niacinamide and vitamin C. Although they're both antioxidants, vitamin C is one ingredient that's not compatible with niacinamide. "Both are very common antioxidants used in a variety of skincare products, but they should not be used one right after the other," says Dr. Marchbein.
Researchers found Niacinamide is an important ingredient in skin lightening, which works to stop the transfer of melanin pigment (responsible for the darkening of the skin) to skin cells (keratinocyte). Niacinamide decreases hyperpigmentation and lightens skin gradually after using it for a long duration.
How long will it take to see the results of niacinamide? While some niacinamide-containing products start to show initial benefits in two weeks, most results will show in four weeks or more.
Niacinamide can also cause you to have excessively dry skin, especially if you're using products that contain other drying ingredients like alcohol or benzoyl peroxide.
What percentage of niacinamide is effective?
"An effective product should have between 2 and 10 percent niacinamide," she explains. Dr. Allenby adds that products with niacinamide concentrations under 5 percent are especially well-tolerated.
Moisturizing ingredients: damp skin
If your facial routine is simple and you're just applying a moisturizer after you cleanse, you'll want to do this ASAP, while your skin is still wet. The same goes for any moisturizing serums you may layer into your routine, like hyaluronic acid, squalene, or niacinamide.
But if you're using two distinct products with these ingredients, wait 15 minutes between applications, or save one for morning use and the other for evening use.
Niacinamide Serum – As most niacinamide serums are water-based, it's best to apply them after cleansing and toning and before oil-based serums or moisturizers. This way, you ensure the highest possible absorption and effectiveness.
That makes niacinamide a great option for improving acne without having to wait through the purging process—which can take several weeks. If you're experiencing breakouts as a result of a product made with niacinamide, take a look at the formula to see if something else might be triggering your skin.
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